Related Experiment Video

Updated: Jan 30, 2026

Assessment of Cerebral Lateralization in Children using Functional Transcranial Doppler Ultrasound fTCD
07:44

Assessment of Cerebral Lateralization in Children using Functional Transcranial Doppler Ultrasound fTCD

Published on: September 27, 2010

20.8K

Reliability of Imaging-Based Diagnosis of Lateral Ventricular Masses in Children

Sanjeev Kumar Pandey1, Sunithi Elizabeth Mani2, Sniya Valsa Sudhakar2

  • 1Department of Neurological Sciences, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

World Neurosurgery
|January 21, 2019
PubMed

Insights

Radiologists accurately diagnosed benign pediatric lateral ventricular tumors but struggled with malignant ones. Interobserver variability was noted, highlighting challenges in imaging diagnosis for these rare pediatric brain tumors.

Area of Science:

  • Pediatric Radiology
  • Neuroradiology
  • Pediatric Neuro-oncology

Background:

  • Lateral ventricular masses in children represent a diverse group of pathologies.
  • Accurate radiologic diagnosis is crucial for guiding treatment and prognosis in pediatric patients.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of radiologic imaging for lateral ventricular masses in children.
  • To identify specific tumor types that are challenging to diagnose pre-operatively.

Main Methods:

  • Retrospective analysis of 43 pediatric patients (8 months to 20 years) with lateral ventricular masses.
  • Review of Magnetic Resonance Imaging (MRI) and contrast-enhanced Computed Tomography (CT) scans by three blinded radiologists.
  • Calculation of inter-radiologist agreement using the Fleiss κ statistic.

Main Results:

  • The study identified common pathologies including subependymal giant cell astrocytoma (SEGA), low-grade astrocytoma, and choroid plexus papilloma.
  • Radiologic diagnosis achieved an overall accuracy of 94.2%, with high accuracy for benign tumors (e.g., SEGA, low-grade gliomas).
  • Malignant tumors (e.g., high-grade gliomas, choroid plexus carcinomas) and cavernous angiomas were difficult to diagnose accurately, and inter-radiologist agreement was only fair (κ = 0.24).

Conclusions:

  • The radiologic diagnosis of pediatric lateral ventricular masses is accurate for benign entities but challenging for malignant neoplasms.
  • Significant interobserver variability exists in the interpretation of these imaging studies.
  • Further refinement of imaging criteria and potentially advanced techniques may improve diagnostic accuracy for difficult-to-diagnose pediatric brain tumors.
Abstract

Keywords:
Brain tumorChildrenDiagnosisLateral ventricleRadiology

More Related Videos

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis08:16

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

33.2K
Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

8.1K

Related Concept Videos

Reliability and Validity01:29

Reliability and Validity

Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
13.9K
Lateralization01:28

Lateralization

Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
1.0K
Distribution Reliability and Automation01:25

Distribution Reliability and Automation

Distribution reliability in electrical power systems is critical for ensuring an uninterrupted power supply to consumers at minimal cost. According to IEEE Standard Terms, reliability is the probability that a device will function without failure over a specified time period or amount of usage. For electric power distribution, this translates to maintaining continuous power supply and addressing customer concerns over power outages. Several indices, as defined by IEEE Standard 1366-2012, are...
512
Nursing Diagnosis01:22

Nursing Diagnosis

Following assessment, a nursing diagnosis is the next step in the nursing process. It begins after the nurse has collected and recorded the patient data. The purpose of diagnosing is to identify how the client responds to actual or potential health processes, identify factors that bestow or that cause health problems, the etiologies, and identify resources or strengths the individual, group, or community can draw on to prevent or resolve problems.
The nursing diagnosis focuses on evidence-based...
4.1K
Atomic Mass01:52

Atomic Mass

Atoms — and the protons, neutrons, and electrons that compose them — are extremely small. For example, a carbon atom weighs less than 2 × 10−23 g. When describing the properties of tiny objects such as atoms, we use appropriately small units of measure, such as the atomic mass unit (amu). The amu was originally defined based on hydrogen, the lightest element, then later in terms of oxygen. Since 1961, it has been defined with regard to the most abundant isotope of carbon, atoms of which...
70.1K
Molar Mass01:54

Molar Mass

The identity of a substance is defined not only by the types of atoms or ions it contains but by the quantity of each type of atom or ion. For example, water, H2O, and hydrogen peroxide, H2O2, are alike in that their respective molecules are composed of hydrogen and oxygen atoms. However, because a hydrogen peroxide molecule contains two oxygen atoms, as opposed to the water molecule, which has only one, the two substances exhibit very different properties.
86.7K