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Related Concept Videos

Data Reporting and Recording01:24

Data Reporting and Recording

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Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
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Types of Reports I: Hands-off Report01:25

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A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
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Types of Reports II: Incident or Occurrence Report01:21

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An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
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Types of Reports III: Telephone and Verbal Reports01:26

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Reporter Genes02:11

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Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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Introduction to Documentation and Reporting01:20

Introduction to Documentation and Reporting

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Documentation is the systematic process of formally recording, maintaining, and communicating information.
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Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
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Porphyria cutanea tarda: a case report.

Hanife Usta Atmaca1, Feray Akbas2

  • 1Istanbul Training and Research Hospital, Internal Medicine Department, University of Health Sciences, Istanbul, Turkey. hanifeusta@yahoo.com.

Journal of Medical Case Reports
|January 22, 2019
PubMed
Summary

Porphyria cutanea tarda is a rare metabolic disorder causing skin blistering and liver issues. Early diagnosis and treatment, like phlebotomy, can reduce complications and health costs.

Keywords:
Liver diseasePorphyria cutanea tardaSkin lesion

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Area of Science:

  • Metabolic disorders
  • Heme biosynthesis pathway
  • Enzyme deficiencies

Background:

  • Porphyrias are rare inherited or acquired metabolic disorders affecting heme biosynthesis.
  • Porphyria cutanea tarda (PCT) results from uroporphyrinogen decarboxylase deficiency, leading to photosensitive byproduct accumulation.
  • PCT impacts the liver and skin, causing blistering, hyperpigmentation, and potential liver damage.

Observation:

  • A 59-year-old man presented with hyperpigmented skin, fatigue, and elevated ferritin and liver function tests.
  • Clinical investigation led to a diagnosis of porphyria cutanea tarda.
  • The patient was treated with phlebotomy.

Findings:

  • Porphyria cutanea tarda is characterized by skin fragility and blistering on sun-exposed areas.
  • Liver involvement in PCT can range from abnormal liver function tests to hepatocellular carcinoma.
  • Iron toxicity is implicated in the pathogenesis of liver damage in PCT.

Implications:

  • PCT requires consideration in the differential diagnosis of liver disease, especially with concurrent skin manifestations.
  • Early diagnosis and treatment of porphyria cutanea tarda are crucial for reducing patient morbidity.
  • Timely intervention can lead to decreased healthcare costs associated with managing PCT complications.