Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

443
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
443
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

694
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
694
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

1.1K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
1.1K
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

402
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
402
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

445
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
445
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

352
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
352

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prenatal diagnosis and postnatal management of perinatal thoracoabdominopelvic tumors: multicenter experience.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2025
Same author

Impact of vancomycin resistance on attributable mortality among Enterococcus faecium bloodstream infections: propensity score analysis of a large, multicentre retrospective study.

The Journal of antimicrobial chemotherapy·2025
Same author

Postoperative risk of infection with klebsiella in adults - a retrospective case-control study.

The Journal of hospital infection·2025
Same author

Hepatoblastoma in a patient with neurofibromatosis type 1: A case report.

Cancer genetics·2025
Same author

Clinical characteristics of women with HIV in the RESPOND cohort: A descriptive analysis and comparison to men.

HIV medicine·2024
Same author

Genomic and epidemiological evidence for the emergence of a <i>L. infantum/L. donovani</i> hybrid with unusual epidemiology in northern Italy.

mBio·2024

Related Experiment Video

Updated: Jan 30, 2026

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.4K

Rhodococcus equi Pneumonia in Kidney Transplant Recipient Affected by Acute Intermittent Porphyria: A Case Report.

G Alfano1, P Ventura2, F Fontana1

  • 1Surgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.

Transplantation Proceedings
|January 22, 2019
PubMed
Summary
This summary is machine-generated.

This case study shows that Rhodococcus equi pneumonia in an acute intermittent porphyria (AIP) patient post-kidney transplant was successfully treated. Azithromycin and meropenem were safe and effective, avoiding porphyria attacks.

More Related Videos

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

5.3K
A Modified Surgical Technique for Kidney Transplantation in Mice
10:38

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

7.2K

Related Experiment Videos

Last Updated: Jan 30, 2026

Robot-Assisted Kidney Transplantation
07:30

Robot-Assisted Kidney Transplantation

Published on: July 19, 2021

4.4K
TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

5.3K
A Modified Surgical Technique for Kidney Transplantation in Mice
10:38

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

7.2K

Area of Science:

  • Infectious Diseases
  • Transplantation Immunology
  • Pharmacology

Background:

  • Rhodococcus equi causes severe pneumonia in immunocompromised individuals.
  • Acute intermittent porphyria (AIP) restricts antibiotic choices due to potential porphyrinogenic effects.
  • Kidney transplant recipients are at risk for opportunistic infections like R. equi.

Observation:

  • A 67-year-old woman with AIP developed R. equi pneumonia 7 months post-kidney transplant.
  • Initial symptoms were nonspecific, but CT revealed a perihilar consolidation with bronchial obstruction.
  • Treatment involved meropenem, azithromycin, and reduced immunosuppression.

Findings:

  • The patient's pneumonia resolved without triggering an AIP attack.
  • Azithromycin and meropenem were identified as safe and effective antibiotics for R. equi in AIP patients.
  • Careful antibiotic selection is crucial to avoid exacerbating AIP.

Implications:

  • This case highlights safe antibiotic options for R. equi infections in AIP patients.
  • Management strategies for opportunistic infections in transplant recipients with AIP can be refined.
  • Clinicians should consider porphyrinogenic potential when prescribing antibiotics for patients with AIP.