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Updated: Jan 30, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Synthesis and characterization of TADDOL-based chiral group six PNP pincer tricarbonyl complexes
Sara R M M de Aguiar1, Christian Schröder-Holzhacker1, Jan Pecak1
11Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9, 1060 Vienna, Austria.
Abstract:
The new chiral PNP pincer ligand N 2,N 6-bis((3aR, 8aR)-2,2-dimethyl-4,4,8,8-tetraphenyltetrahydro[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl)pyridine-2,6-diamine (PNP-TADDOL) was synthesized in 80% isolated yield. Complexes of the type [M(PNP-TADDOL)(CO)3] (M = Cr, Mo, and W) were prepared via a solvothermal approach. This methodology constitutes a fast, simple, and practical synthetic method to obtain complexes of that type in high isolated yields. The X-ray structure of the molybdenum complex is presented.
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