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Pictalignans D-F, three new neolignan derivatives from Selaginella picta
Fei Cheng1,2, Zhen-Xing Zou1,3, Ping-Sheng Xu1
1Xiangya Hospital of Central South University, Changsha, PR China.
Abstract:
Three new neolignan derivatives (1-3), together with three known isolariciresinol derivatives (4-6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-22 cells induced by L-Glutamate in vitro. All compounds displayed potent protective effect on HT-22 cells.
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