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A BW Reporter System for Studying Receptor-Ligand Interactions
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A BW Reporter System for Studying Receptor-Ligand Interactions

Published on: January 7, 2019

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A BW Reporter System for Studying Receptor-Ligand Interactions

Shlomo Elias1, Shira Kahlon2, Alexandra Duev-Cohen2

  • 1Department of Hematology, Hadassah - Hebrew University Medical Center; The Lautenberg Center for General and Tumor Immunology, Department of Immunology and Cancer Research, Institute for Medical Research Israel Canada (IMRIC), Hadassah - Hebrew University Medical Center; elias.shlomo@gmail.com.

Journal of Visualized Experiments : Jove
|January 22, 2019
PubMed
Summary

Researchers developed a reporter system to detect receptor-ligand interactions, even when the ligand is unknown. This sensitive and specific method quantifies receptor activation by measuring interleukin-2 (IL-2) secretion.

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