Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Role of Dexketoprofen/Tramadol in Multimodal Therapy to Prevent Acute Postsurgical and Acute Low Back Pain from Developing into Chronic Pain: A Delphi Consensus Study.

Pain and therapy·2025
Same author

Clinical Benefits of Ibuprofen Arginine: A Narrative Review.

Pain and therapy·2025
Same author

Features and management of osteoarthritis from the perspective of individuals with osteoarthritis: A systematic review of qualitative studies.

Osteoarthritis and cartilage open·2025
Same author

Narrative review of the efficacy and safety of the high-concentration (179mg) capsaicin patch in peripheral neuropathic pain with recommendations for clinical practice and future research.

Pain reports·2025
Same author

Fibromyalgia: do I tackle you with pharmacological treatments?

Pain reports·2025
Same author

Neuropathic Component Characteristics in Chronic Secondary Musculoskeletal Pain After Postmenopausal Osteoporotic Fractures: A Pilot Cross-Sectional Study.

Pain research & management·2025

Related Experiment Video

Updated: Jan 30, 2026

Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
11:26

Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients

Published on: July 14, 2018

17.9K

Fibromyalgia: A misconnection in a multiconnected world?

Serge Perrot1

  • 1Pain Center, Hôpital Cochin, INSERM U987, Paris Descartes University, Paris, France.

European Journal of Pain (London, England)
|January 22, 2019
PubMed
Summary

Fibromyalgia (FM) is reframed as a "misconnection" syndrome, lacking biomarkers and causing invisible suffering. This holistic concept aims to improve patient connection with society, healthcare, and their own bodies.

More Related Videos

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.8K
Synthesis and Exfoliation of Discotic Zirconium Phosphates to Obtain Colloidal Liquid Crystals
08:54

Synthesis and Exfoliation of Discotic Zirconium Phosphates to Obtain Colloidal Liquid Crystals

Published on: May 25, 2016

8.9K

Related Experiment Videos

Last Updated: Jan 30, 2026

Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
11:26

Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients

Published on: July 14, 2018

17.9K
Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.8K
Synthesis and Exfoliation of Discotic Zirconium Phosphates to Obtain Colloidal Liquid Crystals
08:54

Synthesis and Exfoliation of Discotic Zirconium Phosphates to Obtain Colloidal Liquid Crystals

Published on: May 25, 2016

8.9K

Area of Science:

  • Neuroscience
  • Rheumatology
  • Psychiatry

Background:

  • Fibromyalgia (FM) is a controversial condition with unclear pathophysiology, diagnosis, and management.
  • FM is characterized by invisible symptoms, lacking specific biomarkers, leading to patient isolation.

Purpose of the Study:

  • To propose a novel conceptual framework for understanding fibromyalgia as a "misconnection" syndrome.
  • To offer a holistic perspective on FM assessment, management, and patient representation.

Main Methods:

  • Conceptual analysis and synthesis of existing FM research.
  • Development of the "misconnection" framework integrating biological, psychological, and social factors.

Main Results:

  • Fibromyalgia is conceptualized as a misconnection at multiple levels: societal, clinical, pathophysiological, and between brain and body.
  • The "misconnection" concept highlights desynchronization between brain and body, broken patient-physician links, and the need for integrated mind-body assessment and treatment.

Conclusions:

  • The "misconnection" concept provides a new, holistic view of fibromyalgia, improving its assessment, management, and representation.
  • Reconnecting patients with healthcare providers, their bodies, and integrating FM into medical practice are key goals.