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Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
Selective binding of (thio)sulfate and phosphate in water by quaternary ammonium functionalized oligo-ureas
Zhe Huang1, Chuandong Jia, Biao Wu
1Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an 710069, China. jcd2015@nwu.edu.cn.
Abstract:
Recognition of (thio)sulfate and phosphate in aqueous solutions has been demonstrated by using oligo-urea-based receptors functionalized with quaternary ammonium groups. The ammonium groups allow for increased aqueous solubility while simultaneously providing positive coulombic interactions and stronger hydrogen bonding through an inductive effect. This simple and generally applicable modification provides an effective way to bolster the anion binding and water solubility of oligo-urea-based receptors. With a water soluble receptor 2, selective binding of adenosine phosphates was achieved at physiological pH.
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