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Endocrine causes of recurrent pregnancy loss
Selma Amrane1, Rachel McConnell1
1Columbia University Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, New York, NY, United States.
Objective:
To review the available data on endocrine disorders and recurrent pregnancy loss.
Findings:
Our group found that most endocrine disorders do not seem to be correlated with a diagnosis of recurrent pregnancy loss (RPL). The exception to this is testing for thyroid stimulating hormone and thyroid antibodies, which is recommended due to a strong correlation with recurrent pregnancy loss and positive anti-thyroid peroxidase antibodies.
Conclusion:
The available literature supports testing thyroid function and antibodies in women with RPL. Testing for other endocrine disorders is only warranted if otherwise clinically indicated, independent from a history of recurrent pregnancy loss.
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