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Genomic DNA sequence polymorphism of Trypanosoma (Schizotrypanum) cruzi isolates with phenotypic variation
M Castañeda1, S P Craig, C Castro
1Department of Developmental Biology, Universidad Nacional Autónoma de México, México, D.F.
Abstract:
1. Single-copy DNA sequences were analyzed by molecular hybridization to determine both the extent of complementarity and time of evolutionary divergence between three isolates obtained from Argentina, Mexico or Venezuela. 2. The Mexico-Venezuela pair appeared much closer than the Mexico-Argentina pair. 3. The tentative values for time of evolutionary divergence were higher than those estimated previously by allozymic variation.