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Related Concept Videos

Dehydration Synthesis01:15

Dehydration Synthesis

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Overview
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...
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Termination of Translation01:44

Termination of Translation

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The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
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Termination of Translation01:44

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Acid-Catalyzed Dehydration of Alcohols to Alkenes02:35

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In a dehydration reaction, a hydroxyl group in an alcohol is eliminated along with the hydrogen from an adjacent carbon. Here, the products are an alkene and a molecule of water. Dehydration of alcohols is generally achieved by heating in the presence of an acid catalyst. While the dehydration of primary alcohols requires high temperatures and acid concentrations, secondary and tertiary alcohols can lose a water molecule under relatively mild conditions.
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Dehydration of Aldols to Enals: Base-Catalyzed Aldol Condensation01:14

Dehydration of Aldols to Enals: Base-Catalyzed Aldol Condensation

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This lesson delves into the aldol condensation catalyzed by bases, where aldols undergo dehydration to enals. As shown in Figure 1, the β-hydroxy aldehyde formed in a base-catalyzed aldol addition reaction dehydrates on heating to yield an unsaturated carbonyl product, which is commonly referred to as an enal.
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Drag Force and Terminal Speed01:18

Drag Force and Terminal Speed

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An interesting force in everyday life is the force of drag on an object when it is moving in a fluid. Like friction, the drag force always opposes the motion of an object. Unlike simple friction, the drag force is proportional to some function of the velocity of the object in that fluid. This functionality is complicated and depends upon the shape of the object, its size, its velocity, and the fluid it is in. For most large objects, such as cyclists, cars, and baseballs, that are not moving too...
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Articles linked to this work by shared authors, journal, and citation graph.

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[Legal considerations in the care of patients with "terminal dehydration" in Germany].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2020
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[Ethical implications in the therapeutic management of dehydrated patients at the end of life].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2020
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["Terminal" dehydration : Differential diagnosis and body of evidence].

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["Terminal" dehydration, part 2 : Medical indications and therapeutic approach].

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["Terminal" dehydration, part 1 : Differential diagnosis and body of evidence].

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Intraperitoneal bevacizumab for control of malignant ascites due to advanced-stage gastrointestinal cancers: A multicentre double-blind, placebo-controlled phase II study - AIO SUP-0108.

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Related Experiment Video

Updated: Jan 30, 2026

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running
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How to manage terminal dehydration.

U Suchner1, C Reudelsterz2, C Gog3

  • 1Department of anesthesiology and intensive care, Klinikum Darmstadt, Darmstadt, Germany.

Der Anaesthesist
|January 23, 2019
PubMed
Summary
This summary is machine-generated.

Fluid therapy for dehydration in palliative care remains controversial. Clinical assessment guides decisions, with fluid challenges determining if hydration should continue for symptom control or cease if irreversible.

Keywords:
End of life careEvidence-based medicineFluid therapyPalliative careSymptom assessment

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Area of Science:

  • Palliative Care Medicine
  • Geriatrics
  • Clinical Hydration Therapy

Background:

  • Dehydration significantly impacts morbidity and mortality in palliative care patients.
  • Current treatment strategies for dehydration at the end of life lack clear consensus.
  • The term 'end of life care' (ELC) requires more precise definition regarding hydration.

Purpose of the Study:

  • To review the causes of dehydration in end-of-life care, focusing on terminal dehydration.
  • To critically appraise current bedside evaluation and therapeutic approaches for dehydration.
  • To identify areas for future research in palliative hydration management.

Main Methods:

  • Conducted a narrative review of the literature.
  • Searched for relevant articles in English and German published between 1960 and 2018.
  • Critically appraised existing clinical evaluation and treatment options.

Main Results:

  • Evidence does not definitively support or refute fluid therapy during the dying phase.
  • Clinical appearance is the preferred method for evaluating dehydration over invasive procedures.
  • Assessing symptom reversibility via fluid challenge is crucial for treatment decisions.

Conclusions:

  • Cessation of clinically assisted hydration (CAH) may be considered if dehydration is irreversible.
  • Continued fluid management for symptom control is recommended if dehydration symptoms are reversible.
  • Preventing hyperhydration through noninvasive monitoring is essential in end-of-life care.