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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Asthma-IV: Diagnostic and Management01:30

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Asthma-IV: Nursing Management01:30

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
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Breakfast Habits among Schoolchildren in the City of Uruguaiana, Brazil
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Inner-City Asthma in Children.

Pavadee Poowuttikul1, Shweta Saini2, Divya Seth3

  • 1Division of Allergy/Immunology, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, 3950 Beaubien, 4th Floor, Pediatric Specialty Building, Detroit, MI, 48201, USA. ppoowutt@med.wayne.edu.

Clinical Reviews in Allergy & Immunology
|January 23, 2019
PubMed
Summary

Inner-city children face severe asthma, linked to allergens like cockroaches. Interventions targeting allergens and improving care show promise for reducing childhood asthma exacerbations.

Keywords:
AsthmaAsthma Research NetworksAsthma morbidityAsthma risk factorsChildrenInner-citySevere asthma

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Area of Science:

  • Environmental Health
  • Pediatric Allergy
  • Public Health

Background:

  • Inner-city children experience severe, difficult-to-control asthma.
  • Factors like pest exposure, pollutants, poverty, and healthcare access worsen asthma morbidity.
  • National research networks (NCICAS, ICAS, ICAC) were established to improve care for this population.

Purpose of the Study:

  • To investigate the causes and effective interventions for severe asthma in inner-city children.
  • To identify key environmental triggers and their association with asthma exacerbations.
  • To evaluate the impact of various interventions on asthma morbidity in this population.

Main Methods:

  • Analysis of data from the National Cooperative Inner-City Asthma Study (NCICAS), Inner-City Asthma Study (ICAS), and Inner-City Asthma Consortium (ICAC).
  • Investigating the correlation between allergen sensitization/exposure (cockroach, dust mites) and asthma morbidity.
  • Evaluating the efficacy of omalizumab and other interventions like family support, home-based allergen reduction, and school programs.

Main Results:

  • A strong link exists between asthma morbidity and high rates of allergen sensitization, particularly to cockroaches.
  • Reductions in household cockroach and dust mite exposure correlated with decreased asthma morbidity.
  • Omalizumab demonstrated a lowered fall exacerbation rate; further research is ongoing into other contributing factors.

Conclusions:

  • Environmental factors, especially indoor allergens, significantly contribute to severe asthma in inner-city children.
  • Home-based interventions to reduce allergens and tobacco smoke exposure are effective.
  • Multi-faceted approaches, including family support and guideline-driven care, show promise in managing childhood asthma in urban settings.