Related Experiment Video
Updated: Jan 30, 2026
14:43
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
13.5K
Abnormal cervical cytology is associated with preterm delivery: A population based study
Tagrid Jar-Allah1, Cecilia Kärrberg1, Johanna Wiik2,3
1Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Acta Obstetricia Et Gynecologica Scandinavica
|January 23, 2019
Summary
Women with abnormal cervical cytology face a higher risk of preterm delivery. This includes early preterm birth, premature rupture of membranes, and low birthweight, underscoring the importance of cervical health monitoring for obstetric outcomes.
Area of Science:
- Obstetrics and Gynecology
- Reproductive Health
- Cytopathology
Background:
- Cervical intraepithelial neoplasia (CIN) and abnormal cervical cytology are linked to adverse obstetric outcomes, particularly preterm delivery.
- The association between varying grades of abnormal cervical cytology and specific obstetric complications requires further elucidation.
Purpose of the Study:
- To investigate the association between different severities of abnormal cervical cytology and subsequent obstetric outcomes, including preterm delivery.
- To quantify the risk of preterm birth, low birthweight, and other adverse outcomes in women with abnormal cervical cytology compared to those with normal cytology.
Main Methods:
- A historical register-based cohort study in Sweden involving 19,822 women with abnormal cervical cytology and 39,644 matched controls.
- Data linkage between the Swedish National Cervical Screening Registry, Swedish Medical Birth Register, and Statistics Sweden.
- Multivariable log binomial regression analyses were used to assess outcomes such as spontaneous preterm delivery (before 37 and 34 weeks), low birthweight, and preterm premature rupture of membranes.
Main Results:
- Women with abnormal cervical cytology had a significantly higher risk of preterm delivery before 37 weeks (adjusted RR 1.30).
- Higher grades of abnormal cervical cytology were associated with a greater risk of preterm delivery.
- Significant associations were found for early preterm delivery (before 34 weeks), preterm premature rupture of membranes, and low birthweight.
Conclusions:
- Abnormal cervical cytology is associated with an increased risk of preterm delivery and other adverse obstetric outcomes.
- The severity of cervical cytology abnormalities correlates with the magnitude of risk for preterm birth.
- Further research is warranted to explore the role of treatment for cervical abnormalities in mitigating these obstetric risks.
Related Concept Videos
02:04Conservation of Small Populations
17.2K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.2K
02:23Abnormal Proliferation
5.2K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.2K
01:25What is Population Genetics?
64.7K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.7K
01:26Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
654
Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
654
00:30What are Populations and Communities?
37.7K
Overview
37.7K
00:57Population Growth
28.4K
Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.
28.4K