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[Infections and antimicrobial stewardship in cirrhotic patients.]

Valentina Zuccaro1, Raffaele Bruno1

  • 1SC Malattie infettive, Dipartimento Scienze Mediche e Malattie Infettive, Fondazione IRCCS Policlinico San Matteo, Università di Pavia.

Recenti Progressi in Medicina
|January 23, 2019
PubMed

Insights

Antimicrobial stewardship (AS) is crucial for managing infections in cirrhotic patients, preventing antibiotic resistance and improving public health. Implementing AS strategies ensures appropriate, early treatment while reducing costs and healthcare-associated infections.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Public Health

Background:

  • Cirrhotic patients are uniquely vulnerable to infectious complications.
  • These patients are susceptible to healthcare-associated infections due to their 'frail' status.
  • Managing infections in this population requires specialized strategies.

Purpose of the Study:

  • To review recent knowledge on antibiotic stewardship and empiric antibiotic treatment in cirrhotic patients.
  • To highlight the importance of antimicrobial stewardship (AS) in managing infectious complications.
  • To emphasize the role of AS in preventing antibiotic resistance and improving patient outcomes.

Main Methods:

  • This is a review article.
  • Focuses on recent scientific literature and knowledge.
  • Synthesizes information on antimicrobial stewardship principles and practices.

Main Results:

  • Antimicrobial stewardship (AS) is the most appropriate strategy for managing cirrhotic patients with infections.
  • AS facilitates early diagnosis and appropriate therapy, curbing antibiotic overuse.
  • AS policies help prevent the selection and spread of antimicrobial resistance.

Conclusions:

  • Implementing AS rules is essential for the global management of cirrhotic patients.
  • AS contributes to cost reduction and enhances public health strategies.
  • AS ensures better management of infections in 'frail' cirrhotic patients, reducing healthcare-associated infections.

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