Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oxidation of Alcohols02:37

Oxidation of Alcohols

16.0K
In this lesson, the oxidation of alcohols is discussed in depth. The various reagents used for oxidation of primary and secondary alcohols are detailed, and their mechanism of action is provided.
The process of oxidation in a chemical reaction is observed in any of the three forms:
16.0K
Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis02:29

Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis

12.9K
Overview
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
Preparation of Ethers by Alcohol Dehydration
In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
12.9K
Protection of Alcohols02:31

Protection of Alcohols

8.1K
This lesson delves into the concept of protection and deprotection of a functional group fundamental to synthetic organic chemistry. These phenomena are explained in the context of aliphatic and aromatic alcohols.
Protection
It defines a protecting group as the masking agent to make the more reactive species inert to a given set of conditions. This concept is depicted via the illustration of liquid flow through different outlets in an assembly of pipes. The analogy helps to understand the role...
8.1K
Preparation of Alcohols via Substitution Reactions01:38

Preparation of Alcohols via Substitution Reactions

7.4K
Overview
Alcohols can be synthesized from alkyl halides via nucleophilic substitution reactions. The highly polar carbon-halogen bond in the substrate makes halide a good leaving group.  The hydroxide ion or water can act as a nucleophile to take the place of halide and form an alcohol. The substitution reactions occur via two different reaction pathways, SN1 or SN2,  depending on the nature of carbon attached to the halide.
Primary alcohols are synthesized from primary alkyl halides, and the...
7.4K
Esters to Alcohols: Hydride Reductions01:17

Esters to Alcohols: Hydride Reductions

4.8K
Esters are reduced to primary alcohols when treated with a strong reducing agent like lithium aluminum hydride. The reaction requires two equivalents of the reducing agent and proceeds via an aldehyde intermediate.
Lithium aluminum hydride is a source of hydride ions and functions as a nucleophile. The mechanism proceeds in three steps. Firstly, the nucleophilic hydride ion attacks the carbonyl carbon of the ester to form a tetrahedral intermediate. Subsequently, the carbonyl group re-forms,...
4.8K
Esters to Alcohols: Grignard Reaction01:08

Esters to Alcohols: Grignard Reaction

6.1K
The reaction of an ester with a Grignard reagent, followed by hydrolysis of the magnesium alkoxide salt in aqueous acid, yields a tertiary alcohol. In the case of formate esters, secondary alcohols are formed.
The reaction requires two equivalents of the Grignard reagent and introduces two identical alkyl groups, derived from the Grignard reagent, bonded to the hydroxyl-bearing carbon of the alcohol.
The reaction follows the typical nucleophilic acyl substitution mechanism. The Grignard...
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Domestic Deaths from Electrocution.

The Medical journal of the South-West·2017
Same author

Carbon monoxide poisoning; accident, suicide and murder.

The Medico-legal journal·2014
Same author

The case of Stanley Setty.

The Medico-legal journal·2014
Same author

An outbreak of infection due to Salm. typhi-murium.

British medical journal·2010
Same author

Methyl iodide poisoning.

British journal of industrial medicine·2010
Same author

ACUTE TONSILLITIS: AN ACCOUNT OF SOME RECENT STREPTOCOCCAL INFECTIONS.

British medical journal·2010
Same journal

A Change of Government and Its Effect on the NHS Hospital Outpatient Service.

Journal of the Royal College of Physicians of London·2019
Same journal

Erratum: Model for the Organisation of a Community-Based Rehabilitation Service.

Journal of the Royal College of Physicians of London·2019
Same journal

Telemedicine and beyond.

Journal of the Royal College of Physicians of London·2019
Same journal

Palliative Care in General Medicine.

Journal of the Royal College of Physicians of London·2019
Same journal

Medical Negligence.

Journal of the Royal College of Physicians of London·2019
Same journal

In Response.

Journal of the Royal College of Physicians of London·2019
See all related articles

Related Experiment Video

Updated: Jan 30, 2026

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
08:45

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis

Published on: November 8, 2024

1.3K

Alcohol

F E Camps1

  • 1Professor of Forensic Medicine, The London Hospital Medical College, London.

Journal of the Royal College of Physicians of London
|January 23, 2019
PubMed
Summary

No abstract available in PubMed .

More Related Videos

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

3.6K
The FlyBar: Administering Alcohol to Flies
10:29

The FlyBar: Administering Alcohol to Flies

Published on: May 18, 2014

11.3K

Related Experiment Videos

Last Updated: Jan 30, 2026

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
08:45

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis

Published on: November 8, 2024

1.3K
The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

3.6K
The FlyBar: Administering Alcohol to Flies
10:29

The FlyBar: Administering Alcohol to Flies

Published on: May 18, 2014

11.3K