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Spontaneous Brain Activity Predicts Task-Evoked Activity During Animate Versus Inanimate Touch.

Andrea Scalabrini1, Sjoerd J H Ebisch2,3, Zirui Huang4

  • 1Department of Psychological, Health and Territorial Sciences (DiSPuTer), G. d'Annunzio University of Chieti-Pescara, Via dei Vestini 33, Chieti (CH), Italy.

Cerebral Cortex (New York, N.Y. : 1991)
|January 23, 2019
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Summary

Spontaneous brain activity, measured by the power law exponent (PLE), influences how we process animate versus inanimate stimuli. This brain activity in the perigenual anterior cingulate cortex (PACC) helps tune our perception of the animate world.

Keywords:
animate stimuliperigenual anterior cingulate cortexscale-free brain dynamicsspontaneous brain activitytask evoked activity

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Area of Science:

  • Neuroscience
  • Cognitive Science
  • Brain Activity Analysis

Background:

  • Spontaneous brain activity exhibits complex temporal structures with scale-free properties.
  • The brain's resting-state activity may modulate responses to external stimuli.

Purpose of the Study:

  • To investigate if spontaneous brain activity modulates neural responses to animate versus inanimate stimuli.
  • To explore the role of brain's intrinsic activity in distinguishing between self-generated and external interactions.

Main Methods:

  • Participants interacted with animate (real hand) and inanimate (mannequin hand) stimuli.
  • Task-evoked neural activity and functional connectivity were measured using fMRI.
  • Power law exponent (PLE) of spontaneous brain activity was analyzed in key brain regions.

Main Results:

  • Participants perceived animate stimuli as more synchronous and relevant than inanimate ones.
  • Animate vs. inanimate interactions modulated activity in posterior insula, medial prefrontal cortex, and medial superior frontal gyrus.
  • Increased functional connectivity between posterior insula and perigenual anterior cingulate cortex (PACC) was observed during animate interactions.
  • Spontaneous brain activity's PLE in PACC correlated with task-evoked activity, distinguishing animate from inanimate stimuli.

Conclusions:

  • Spontaneous brain activity in the PACC is linked to the processing of animate versus inanimate stimuli.
  • The brain's intrinsic activity may be tuned to better engage with the animate environment.
  • Findings suggest a mechanism by which the brain aligns itself with animate surroundings through spontaneous activity modulation.