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Updated: Jan 30, 2026

Corticospinal Excitability Modulation During Action Observation
Published on: December 31, 2013
Long-lasting actions of somatostatin on pyramidal cell excitability in the mouse cingulate cortex
Therese Riedemann1, Bernd Sutor1
1Biomedical Center, Ludwig-Maximilians-Universität, Physiological Genomics, Großhaderner Str. 9, 82152 Planegg-Martinsried, Germany.
Abstract:
Many neurological diseases are related to disturbances of somatostatin- (SOM-) expressing interneurons in the cingulate cortex. Therefore, their role within the circuitry of the cingulate cortex needs to be investigated. We describe here the physiological time course of SOM effects onto pyramidal cell excitability and action potential discharge pattern. Furthermore, we show that the GRK2 inhibitor Gallein had no effect on the reduced SOM-induced response following repetitive SOM applications.
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