Antifouling (Bio)materials for Electrochemical (Bio)sensing
Susana Campuzano1, María Pedrero2, Paloma Yáñez-Sedeño3
1Departamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, E-28040 Madrid, Spain. susanacr@quim.ucm.es.
Biomaterial-based strategies using polymers, hydrogels, and peptides effectively combat biofouling on electrochemical biosensors. These antifouling approaches ensure reliable sensing in complex biological samples and harsh environments.
Area of Science:
- Electrochemistry
- Materials Science
- Biotechnology
Background:
- Biofouling, caused by protein adsorption and compound precipitation, compromises electrochemical biosensor accuracy.
- Developing antifouling interfaces is crucial for reliable electrochemical biosensing in complex samples.
Purpose of the Study:
- To review and critically discuss biomaterial-based antifouling strategies for electrochemical biosensors.
- To highlight recent advancements and applications in overcoming biofouling challenges.
Main Methods:
- Review of literature on antifouling strategies using polymers, hydrogels, peptides, and self-assembled monolayers.
- Analysis of strategies involving carbon materials, nanoparticles, and electrochemical activation.
Main Results:
- Biomaterial-based strategies demonstrate success in minimizing biofouling.
- Reported methods enable reliable sensing of challenging analytes in biofluids and harsh conditions.
Conclusions:
- Biomaterial-based antifouling strategies are effective for electrochemical biosensing.
- Further research is needed to address unmet challenges and explore future prospects in antifouling technologies.
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