Related Experiment Video
Updated: Jan 30, 2026
In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors
Published on: December 17, 2013
Udder and teat conformational risk factors for elevated somatic cell count and clinical mastitis in New York
Asha M Miles1, Jessica A A McArt2, Francisco A Leal Yepes1
1Department of Animal Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY, 14853, United States.
Our primary objective was to identify udder and teat conformational risk factors associated with the occurrence of elevated somatic cell count (SCC) and clinical mastitis using a prospective cohort study design with careful assessment of exposure and disease outcomes. Mastitis prevalence was evaluated by parity across 6 sampling periods representing key physiological transitions during lactation: 0-1 day in milk (DIM), 3-5 DIM, 10-14 DIM, 50-60 DIM, 90-110 DIM, and 210-230 DIM. Cows were scored for front and rear teat length, width, end shape, and placement, fore udder attachment, udder cleft, udder depth, rear udder height, and rear udder width. Two independent multivariable logistic regression models were used to generate odds ratios (OR) for elevated SCC (≥ 200,000 cells/ml) and farm-diagnosed clinical mastitis. We identified that loose fore udder attachment (reference level: strong fore udder attachment, OR = 2.1, 95% confidence interval (CI) = 1.2-3.8) and flat teat end shape (reference level: round teat end shape, OR = 1.4, 95% CI = 1.1-1.9) increased the odds of an elevated SCC event, whereas a negative California Mastitis Test score at 0-1 DIM decreased the odds of an elevated SCC event (OR = 0.6, 95% CI = 0.4 to 0.8). Loose fore udder attachment (reference level: strong fore udder attachment, OR = 3.7, 95% CI = 1.3-10.7), flat teat end shape (reference level: round teat end shape, OR = 1.5, 95% CI = 1.0-2.4), low rear udder height (reference level: intermediate rear udder height, OR = 2.8, 95% CI = 0.3-6.2), and increasing rear teat width (OR = 2.2, 95% CI = 1.2-4.4) heightened the odds of developing clinical mastitis. We identified that within our study cohort, loose fore udder attachment and flat teat ends had an important association with increased odds of both an elevated SCC event and clinical mastitis diagnosis. The identification of these udder and teat conformational risk factors for mastitis can provide farmers an effective and inexpensive tool to manage mastitis.
Our primary objective was to identify udder and teat conformational risk factors associated with the occurrence of elevated somatic cell count (SCC) and clinical mastitis using a prospective cohort study design with careful assessment of exposure and disease outcomes. Mastitis prevalence was evaluated by parity across 6 sampling periods representing key physiological transitions during lactation: 0-1 day in milk (DIM), 3-5 DIM, 10-14 DIM, 50-60 DIM, 90-110 DIM, and 210-230 DIM. Cows were scored for front and rear teat length, width, end shape, and placement, fore udder attachment, udder cleft, udder depth, rear udder height, and rear udder width. Two independent multivariable logistic regression models were used to generate odds ratios (OR) for elevated SCC (≥ 200,000 cells/ml) and farm-diagnosed clinical mastitis. We identified that loose fore udder attachment (reference level: strong fore udder attachment, OR = 2.1, 95% confidence interval (CI) = 1.2-3.8) and flat teat end shape (reference level: round teat end shape, OR = 1.4, 95% CI = 1.1-1.9) increased the odds of an elevated SCC event, whereas a negative California Mastitis Test score at 0-1 DIM decreased the odds of an elevated SCC event (OR = 0.6, 95% CI = 0.4 to 0.8). Loose fore udder attachment (reference level: strong fore udder attachment, OR = 3.7, 95% CI = 1.3-10.7), flat teat end shape (reference level: round teat end shape, OR = 1.5, 95% CI = 1.0-2.4), low rear udder height (reference level: intermediate rear udder height, OR = 2.8, 95% CI = 0.3-6.2), and increasing rear teat width (OR = 2.2, 95% CI = 1.2-4.4) heightened the odds of developing clinical mastitis. We identified that within our study cohort, loose fore udder attachment and flat teat ends had an important association with increased odds of both an elevated SCC event and clinical mastitis diagnosis. The identification of these udder and teat conformational risk factors for mastitis can provide farmers an effective and inexpensive tool to manage mastitis.
Related Concept Videos
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
01:20Conformity
03:12Freezing Point Depression and Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
01:29Somatic to iPS Cell Reprogramming
02:20Conformations of Butane
02:21Cancers Originate from Somatic Mutations in a Single Cell