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Updated: Jan 30, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Comparative assessment of drug-induced sleep endoscopy scoring systems in pediatric sleep apnea
Joseph Tejan1, Melecio Medina1, Seckin O Ulualp1,2
1Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.
Insights
Current drug-induced sleep endoscopy (DISE) scoring systems do not differentiate obstructive sleep apnea (OSA) severity in children. Further research is needed to develop a universally accepted pediatric DISE scoring system for accurate OSA assessment.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Respiratory Medicine
Background:
- Drug-induced sleep endoscopy (DISE) is utilized to assess upper airway obstruction in obstructive sleep apnea (OSA).
- Existing DISE scoring systems lack universal acceptance, particularly for pediatric populations.
- A dedicated, universally accepted DISE scoring system for children with OSA is needed.
Purpose of the Study:
- To evaluate the utility of current DISE scoring systems in assessing pediatric obstructive sleep apnea (OSA).
- To determine if existing DISE scoring systems can differentiate between varying degrees of OSA severity in children.
- To explore the influence of age, obesity, and OSA severity on DISE scores in pediatric patients.
Main Methods:
- Retrospective chart review of surgically naive, healthy children diagnosed with OSA who underwent DISE.
- Literature review to identify existing DISE scoring systems used in pediatric OSA.
- Analysis of DISE recordings by blinded reviewers to assess the effect of age, obesity, OSA severity, and oxygen nadir on DISE scores.
Main Results:
- Sixty-eight pediatric patients (19 months–18 years) were included; 43 were obese.
- DISE scoring systems did not reveal significant differences across mild, moderate, and severe OSA categories (P > .05).
- DISE scores showed no significant variation among different age and weight categories (P > .05).
Conclusions:
- Current DISE scoring systems are insufficient to differentiate OSA severity in pediatric patients.
- Findings suggest a need for a universally applicable pediatric-specific DISE scoring system.
- Development of a standardized pediatric DISE scoring system is crucial for accurate OSA evaluation in children.
Objectives/Hypothesis:
A wide variety of drug-induced sleep endoscopy (DISE) scoring systems has been used to evaluate sites of upper airway obstruction in children and adults; however, a universally accepted DISE scoring system dedicated to children has not been developed. We evaluated the utility of DISE scoring systems in the assessment of obstructive sleep apnea (OSA) using a single cohort of pediatric patients.
Study Design:
Retrospective chart review.
Methods:
The medical records of surgically naïve-healthy children with OSA who had undergone DISE were reviewed. Information about demographics, past medical history, and severity of OSA were obtained. A literature review was conducted to identify DISE scoring systems used in children with OSA. Recordings of DISE were analyzed without knowledge of patient information and severity of OSA. The effect of age, obesity, severity of OSA, and oxygen nadir on DISE score was assessed.
Results:
Sixty-eight patients (46 male, 22 female, age range: 19 months-18 years) were included. Forty-three patients were obese and 25 were nonobese. The severity of OSA was mild in 12 patients, moderate in 13 patients, and severe in 43 patients. DISE scoring systems did not document differences among the groups of patients with mild OSA, moderate OSA, and severe OSA (P > .05). DISE scores were not different among the studied age and weight categories (P > .05).
Conclusions:
The DISE scoring systems did not show differences in DISE scores in surgically naïve-healthy children with varying age, weight, and OSA severity categories. Our findings provide preliminary evidence for the need of a universally applicable pediatric DISE scoring system for OSA.
Level Of Evidence:
4 Laryngoscope, 129:2195-2198, 2019.
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