Related Experiment Video
Updated: Jan 30, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
Published on: April 3, 2014
Indacyclopentadienes and Aromatic Indacyclopentadienyl Dianions: Synthesis and Characterization
Yongliang Zhang1, Zhenqiang Yang2, Wen-Xiong Zhang1
1Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing, 100871, P.R. China.
Abstract:
A series of unprecedented metallacycles of indium, including indacyclopentadienes (2), spiro indacyclopentadienes (3), aromatic indacyclopentadienyl dianions with an In-Li bond (4), and aromatic indacyclopentadienyl dianions with an In-In bond (5), were synthesized and structurally characterized by single-crystal X-ray structural analysis for the first time. Both indacyclopentadienes 2 and 3 were synthesized by reaction of 1,4-dilithio-1,3-butadienes with InCl3 . Structural transformations between 2 and 3 were observed. Reduction of indacyclopentadienes 2 with an excess amount of lithium afforded aromatic indacyclopentadienyl dianions 4 with an In-Li bond or 5 with an In-In bond, respectively, depending on the substituents on the ring. The aromatic character of 4 and 5 was confirmed by both experimental measurements and theoretical analysis.
Related Concept Videos
Nucleophilic Aromatic Substitution of Aryldiazonium Salts: Aromatic SN1
In the Sandmeyer reaction, for example, the diazonio group is replaced by a chloro, bromo,...
Dehydration Synthesis
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...
Synthesis and Decomposition Reactions
Aromatic Compounds: Overview
In 1825, Faraday isolated...
Basicity of Aromatic Amines
Lagging Strand Synthesis
There are several major differences between synthesis of the leading strand and synthesis of the lagging strand. 1) Leading strand synthesis happens in the direction of replication fork opening, whereas lagging strand synthesis happens in the...

