Risk factors for vascular catheter-related bloodstream infections in pediatric intensive care units

Fabiola Peixoto Ferreira La Torre1, Gabriel Baldanzi2, Eduardo Juan Troster3,4

  • 1Departamento de Pediatria, Faculdade de Ciências Médicas, Santa Casa de São Paulo - São Paulo (SP), Brasil.

Insights

Prolonged central venous catheter use and multiple catheter insertions increase the risk of central line-associated blood stream infections (CLABSI) in pediatric intensive care units. These findings highlight key factors for preventing CLABSI in critically ill children.

Area of Science:

  • Pediatric Intensive Care
  • Infectious Diseases
  • Epidemiology

Background:

  • Central line-associated blood stream infections (CLABSI) are a significant concern in pediatric intensive care units (PICUs).
  • Understanding risk factors is crucial for developing effective prevention strategies.

Purpose of the Study:

  • To identify risk factors for CLABSI in PICUs.
  • To determine the incidence and causes of CLABSI in PICUs with varying characteristics.

Main Methods:

  • Prospective cohort study involving 728 patients across three different hospital types.
  • Included patients aged 1 month to 18 years with central venous catheters for over 24 hours.
  • Data analyzed using SPSS version 13.0 to compare patients with and without CLABSI.

Main Results:

  • CLABSI incidence rate was 3.9 per 1000 central venous catheter-days, varying by hospital.
  • Independent risk factors for CLABSI included longer central venous catheter duration (OR: 1.07) and use of multiple catheters (OR: 2.59).
  • Mortality rate was 11.1%, with a higher rate in CLABSI patients (12.9%).

Conclusions:

  • Extended use of central venous catheters is a primary risk factor for CLABSI in PICUs.
  • Utilizing more than one central venous catheter concurrently significantly elevates CLABSI risk.
  • These findings underscore the importance of judicious catheter use in pediatric critical care settings.
Abstract

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