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Recommendations for hypofractionated whole-breast irradiation
, Nilceana Maya Aires Freitas1, Arthur Accioly Rosa2
1. Radiotherapy Department of the Araújo Jorge Hospital of the Góias State Association Against Cancer, Goiânia/GO, Brasil.
Summary
This consensus provides recommendations for hypofractionated whole-breast radiotherapy (RT), a safe and effective breast cancer treatment. It addresses key considerations for its optimal use in Brazil.
Area of Science:
- Oncology
- Radiotherapy
- Medical Physics
Background:
- Hypofractionated whole-breast radiotherapy (RT) is an evolving treatment modality.
- Establishing clear guidelines is crucial for its safe and effective application.
- The Brazilian Society of Radiotherapy (SBRT) initiated this consensus to address specific clinical scenarios.
Purpose of the Study:
- To develop a consensus recommendation for hypofractionated whole-breast radiotherapy (RT).
- To define optimal indications and safety parameters for this RT technique.
- To address controversies and contraindications in various patient subgroups.
Main Methods:
- A consensus meeting was convened by the Brazilian Society of Radiotherapy (SBRT).
- Discussions focused on specific clinical situations including chemotherapy, lymphatic drainage, post-mastectomy, boost, patient age, breast size, and DCIS.
- A consensus was achieved with at least 75% agreement among panel members.
Main Results:
- Recommendations were formulated based on scientific evidence, graded as weak, medium, or strong.
- Specific guidance was developed for hypofractionated RT in diverse clinical contexts.
- The consensus addresses contraindications and specific patient populations.
Conclusions:
- This consensus provides valuable guidance for Brazilian radiotherapy experts on hypofractionated RT.
- It establishes the technique as a viable and safe alternative within the national healthcare context.
- The recommendations aim to optimize the use of hypofractionated RT for improved patient outcomes.

