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Recommendations for hypofractionated whole-breast irradiation.

, Nilceana Maya Aires Freitas1, Arthur Accioly Rosa2

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This consensus provides recommendations for hypofractionated whole-breast radiotherapy (RT), a safe and effective breast cancer treatment. It addresses key considerations for its optimal use in Brazil.

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Area of Science:

  • Oncology
  • Radiotherapy
  • Medical Physics

Background:

  • Hypofractionated whole-breast radiotherapy (RT) is an evolving treatment modality.
  • Establishing clear guidelines is crucial for its safe and effective application.
  • The Brazilian Society of Radiotherapy (SBRT) initiated this consensus to address specific clinical scenarios.

Purpose of the Study:

  • To develop a consensus recommendation for hypofractionated whole-breast radiotherapy (RT).
  • To define optimal indications and safety parameters for this RT technique.
  • To address controversies and contraindications in various patient subgroups.

Main Methods:

  • A consensus meeting was convened by the Brazilian Society of Radiotherapy (SBRT).
  • Discussions focused on specific clinical situations including chemotherapy, lymphatic drainage, post-mastectomy, boost, patient age, breast size, and DCIS.
  • A consensus was achieved with at least 75% agreement among panel members.

Main Results:

  • Recommendations were formulated based on scientific evidence, graded as weak, medium, or strong.
  • Specific guidance was developed for hypofractionated RT in diverse clinical contexts.
  • The consensus addresses contraindications and specific patient populations.

Conclusions:

  • This consensus provides valuable guidance for Brazilian radiotherapy experts on hypofractionated RT.
  • It establishes the technique as a viable and safe alternative within the national healthcare context.
  • The recommendations aim to optimize the use of hypofractionated RT for improved patient outcomes.