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Updated: Jan 30, 2026

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models
Published on: June 20, 2025
Studying the lung dose uncertainty during chest CT scans using phantoms with statistical lung volumes and shapes
Atiyeh Ebrahimi-Khankook1, Parisa Akhlaghi2,3, Alireza Vejdani-Noghreiyan1
1Physics Department, Faculty of Sciences, University of Neyshabur, Neyshabur, Iran.
Abstract:
In recent years, there has been increasing interest in constructing a series of deformable phantoms which follow the statistical distributions of some anatomical variations, known as 'statistical phantoms'. The main purpose of this study was to develop statistical phantoms by considering the variations in lung volume and shape, in order to evaluate the lung dose uncertainty for individuals undergoing chest computed tomography. Calculations were performed for 100 statistical lung volume phantoms and 70 statistical lung shape phantoms at tube voltages of 80 and 120 kVp, with the use of Monte Carlo MCNP code. The obtained results indicate that dose fluctuations for low tube voltage (80 kVp) are higher than those at 120 kVp. Moreover, it shows that the impact of statistical variations in lung volume on dose discrepancy (5% to 7%) is higher than the impact of statistical lung shape variations (around 2%).
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