Related Experiment Video

Updated: Jan 30, 2026

Bottlenose Dolphin Tursiops truncatus Spermatozoa: Collection, Cryopreservation, and Heterologous In Vitro Fertilization
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Leukopenia induced by micafungin in a bottlenose dolphin (Tursiops truncatus): a case report

Yoshito Ohno1, Yuichiro Akune1, Hiroshi Nitto1

  • 1Port of Nagoya Public Aquarium, 1-3 Minato-machi, Minato-ku, Nagoya, Aichi 455-0033, Japan.

The Journal of Veterinary Medical Science
|January 25, 2019
PubMed

Insights

This study reports a bottlenose dolphin treated for Aspergillus pneumonia experienced low body temperature and white blood cell counts due to micafungin. Granulocyte colony-stimulating factor (G-CSF) successfully resolved these adverse effects.

Area of Science:

  • Veterinary Medicine
  • Marine Mammal Health
  • Mycology

Background:

  • Aspergillus fumigatus is a common fungal pathogen causing pneumonia in marine mammals.
  • Antifungal treatments are crucial for managing invasive fungal infections in cetaceans.
  • Micafungin is an echinocandin antifungal agent used in veterinary medicine.
Keywords:
G-CSFbottlenose dolphinfungal pneumonialeukopeniamicafungin

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