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Hydrogels Based on Dynamic Covalent and Non Covalent Bonds: A Chemistry Perspective
Francesco Picchioni1, Henky Muljana2,3
1Department of Chemical Engineering, Engineering and Technology Institute Groningen (ENTEG), University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands. F.Picchioni@rug.nl.
Gels (Basel, Switzerland)
|January 25, 2019
Summary
Hydrogels using reversible covalent bonds offer tunable properties for advanced applications. This review focuses on recent chemical advancements, enabling tailored material design for self-healing and drug delivery systems.
Area of Science:
- Polymer Chemistry
- Materials Science
- Biomedical Engineering
Background:
- Hydrogels based on reversible covalent bonds are gaining traction in academia and industry.
- The reversible nature of these bonds imparts unique properties like self-healing and responsiveness to stimuli.
- These characteristics are vital for biomedical applications, including drug delivery.
Purpose of the Study:
- To review recent advancements (last five years) in hydrogels utilizing reversible covalent bonds.
- To focus on the underlying chemistry of these systems.
- To provide a foundation for molecular designers to create novel hydrogels with specific properties.
Main Methods:
- Literature review of scientific publications from the past five years.
- Focus on the chemical principles governing reversible covalent bond formation in hydrogels.
- Analysis of structure-property relationships in these advanced materials.
Main Results:
- Identification of emerging trends and novel chemistries in reversible covalent hydrogels.
- Highlighting the versatility in designing hydrogel networks with tunable properties.
- Demonstration of the potential for self-healing and controlled release functionalities.
Conclusions:
- Reversible covalent hydrogels offer a versatile platform for developing advanced materials.
- Continued exploration of their chemistry is crucial for unlocking new applications.
- This review serves as a guide for designing next-generation hydrogels for targeted uses.
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