Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cochlear blood flow: measurement techniques.

A L Nuttall1

  • 1Kresge Hearing Research Institute, University of Michigan, Ann Arbor 48109-0506.

American Journal of Otolaryngology
|November 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outer hair cell driven reticular lamina mechanical distortion in living cochleae.

Hearing research·2021
Same author

Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter.

American journal of physiology. Heart and circulatory physiology·2011
Same author

Effect of capsaicin on potassium conductance and electromotility of the guinea pig outer hair cell.

Hearing research·2010
Same author

Effect of salicylate on KCNQ4 of the guinea pig outer hair cell.

Journal of neurophysiology·2010
Same author

The influence of loud sound stress on expression of osmotic stress protein 94 in the murine inner ear.

Neuroscience·2008
Same author

Spontaneous basilar membrane oscillation and otoacoustic emission at 15 kHz in a guinea pig.

Journal of the Association for Research in Otolaryngology : JARO·2005
Same journal

Letter to the editor regarding "Development of a novel self-assessment tool following endoscopic sinus surgery in the management of chronic rhinosinusitis".

American journal of otolaryngology·2026
Same journal

Re: Sarcopenia and postoperative morbidity in head and neck cancer: a systematic review and meta-analysis.

American journal of otolaryngology·2026
Same journal

Epistaxis burden in hereditary hemorrhagic telangiectasia: Validation and refinement of the NOSE-HHT.

American journal of otolaryngology·2026
Same journal

An assessment of pharmacologic deep vein thrombosis prophylaxis on head and neck free flap outcomes.

American journal of otolaryngology·2026
Same journal

Rapid improvement of nasal obstruction after treatment with a non-vasoconstrictive osmotic nasal spray: A prospective observational study.

American journal of otolaryngology·2026
Same journal

Evaluation of systemic inflammation in sinonasal inverted papilloma using hematological and biochemical markers.

American journal of otolaryngology·2026
See all related articles

Measuring inner ear blood flow presents unique challenges. This review discusses current methods for cochlear blood circulation measurement, highlighting technical issues and the importance of combined approaches for accurate interpretation.

Area of Science:

  • Otolaryngology
  • Cardiovascular Physiology
  • Biomedical Engineering

Background:

  • Assessing inner ear microvascular function is critical for understanding auditory and vestibular health.
  • Existing methods for measuring cochlear blood flow face significant technical and methodological limitations.
  • Difficulties in measurement complicate the interpretation of experimental findings in inner ear research.

Purpose of the Study:

  • To review and discuss the primary methods for measuring cochlear blood circulation.
  • To identify and elaborate on the technical challenges associated with each measurement technique.
  • To emphasize the utility of integrating multiple measurement techniques to overcome interpretive difficulties.

Main Methods:

  • Laser Doppler Flowmetry (LDF) for real-time blood flow assessment.

Related Experiment Videos

  • Hydrogen clearance techniques for measuring tissue perfusion.
  • Microsphere techniques for quantifying regional blood flow.
  • Doppler ultrasonography for non-invasive vascular assessment.

    • Main Results:

    • Each method possesses inherent technical limitations affecting data reliability and interpretation.
    • Laser Doppler Flowmetry offers high temporal resolution but can be influenced by tissue properties.
    • Hydrogen clearance provides a measure of perfusion but requires invasive procedures.
    • Combined approaches, integrating data from multiple methods, are essential for robust interpretation.

    Conclusions:

    • Accurate measurement of inner ear blood flow requires careful consideration of methodological limitations.
    • Employing a combination of techniques enhances the reliability and validity of cochlear microvascular research.
    • Further development of non-invasive and precise measurement tools is needed for advancing inner ear research.