Practice Implications of Expanded Genetic Testing in Oncology

Area of Science:

• Oncology
• Medical Genetics
• Healthcare Delivery

Background:

• Genetic testing is expanding in oncology.
• Provider experiences with these changes are not well understood.

Purpose of the Study:

• To explore oncologists' and cancer genetics professionals' experiences with evolving genetic testing norms.
• To identify implications for patient care.

Main Methods:

• Qualitative study involving interviews with 22 key informants (oncologists and cancer genetics professionals).

Main Results:

• Germline genetic test results are crucial for cancer treatment decisions.
• Oncologists prefer ordering genetic tests directly.
• Cancer gene panels are rapidly adopted.
• Challenges identified in informed consent, result interpretation, and patient management.

Conclusions:

• The transition of genetic testing from specialists to oncologists necessitates attention.
• Practice guidelines and provider training need to address emerging issues in genetic testing delivery.