Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Levobunolol compared with timolol: a four-year study.

O Geyer1, M Lazar, G D Novack

  • 1Department of Ophthalmology, Ichilove Medical Center, Sackler School of Medicine, University of Tel Aviv, Israel.

The British Journal of Ophthalmology
|December 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence of Spin-Interference Effects in Exclusive J/ψ→e^{+}e^{-} Photoproduction in Ultraperipheral Heavy-Ion Collisions.

Physical review letters·2026
Same author

First Observation of Deuteron-Λ Correlations at RHIC.

Physical review letters·2026
Same author

Observation of Charmonium Sequential Suppression in Heavy-Ion Collisions at the Relativistic Heavy Ion Collider.

Physical review letters·2026
Same author

Energy Independence of the Collins Asymmetry in p^{↑}p Collisions.

Physical review letters·2026
Same author

Precision Measurement of Net-Proton-Number Fluctuations in Au+Au Collisions at RHIC.

Physical review letters·2025
Same author

Measurement of Two-Point Energy Correlators within Jets in p+p Collisions at sqrt[s]=200  GeV.

Physical review letters·2025

Levobunolol and timolol ophthalmic solutions effectively reduce high intraocular pressure (IOP). This study found both drugs equally safe and effective for long-term IOP management in glaucoma patients.

Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Elevated intraocular pressure (IOP) is a significant risk factor for glaucoma.
  • Effective long-term IOP management is crucial for preventing optic nerve damage.

Purpose of the Study:

  • To compare the efficacy and safety of levobunolol and timolol ophthalmic solutions in reducing intraocular pressure.
  • To evaluate the long-term effects of these treatments on IOP control.

Main Methods:

  • A double-masked, randomized trial involving 51 patients with raised IOP.
  • Administration of 0.5% levobunolol, 1% levobunolol, or 0.5% timolol twice daily to both eyes for up to four years.

Main Results:

  • All three treatment groups achieved significant IOP reductions, exceeding 8.8 mmHg.

Related Experiment Videos

  • Levobunolol (0.5% and 1%) and timolol (0.5%) demonstrated comparable efficacy in lowering mean IOP.
  • No significant differences in safety profiles were observed between levobunolol and timolol.

    • Conclusions:

    • Levobunolol is as safe and effective as timolol for the long-term management of elevated intraocular pressure.
    • Levobunolol offers a viable alternative to timolol for patients requiring sustained IOP reduction.