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Serotonin Syndrome with Atypical Hypernatremia.
Ashley N Rubin1, Eduardo D Espiridion2, Mohamad Kattan3
1Family Medicine, West Virginia School of Osteopathic Medicine, Lewisburg, USA.
Cureus
|January 26, 2019
Summary
Serotonin syndrome is increasing, posing risks. Early diagnosis using established criteria is vital, even with complex patient histories, to prevent severe outcomes.
Area of Science:
- Neuroscience
- Clinical Toxicology
Background:
- Serotonin syndrome (SS) incidence is rising in the United States.
- Awareness of diagnostic criteria and a low threshold for utilization are crucial for preventing morbidity and mortality.
Observation:
- A 64-year-old female presented with altered mental status.
- Her symptoms suggested SS, but complex medical history and elevated sodium levels delayed diagnosis.
Findings:
- SS diagnosis can be challenging, especially with comorbidities and polypharmacy.
- Medication toxicities must remain a high priority in differential diagnoses.
Implications:
- Thorough history, physical examination, and medication reconciliation are cost-effective diagnostic tools.
- Prompt identification and management of SS are essential for patient safety.
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