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Updated: Jan 30, 2026

A Modular Microfluidic Technology for Systematic Studies of Colloidal Semiconductor Nanocrystals
Published on: May 10, 2018
Nanocrystals: A perspective on translational research and clinical studies
Maria Jarvis1, Vinu Krishnan2, Samir Mitragotri2
1Dept. of Bioengineering Rice University Houston TX 77030.
Abstract:
Poorly soluble small molecules typically pose translational hurdles owing to their low solubility, low bioavailability, and formulation challenges. Nanocrystallization is a versatile method for salvaging poorly soluble drugs with the added benefit of a carrier-free delivery system. In this review, we provide a comprehensive analysis of nanocrystals with emphasis on their clinical translation. Additionally, the review sheds light on clinically approved nanocrystal drug products as well as those in development.
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