[Effects of SPR periodontal basic therapy on cervical crevicular fluid C-reactive protein in patients with chronic...

To investigate the effect of SPR periodontal basic treatment on periodontal inflammation control and inflammation index C-reactive protein in gingival crevicular fluid in patients with chronic periodontitis.

Eighty patients with chronic periodontitis in the pre-clinical trial population were included in this study for subgroup analysis. Repeated measures analysis of variance was used to compare the changes of periodontal index (including average probing depth, clinical adhesion level, and sulcus bleeding index) and gingival crevicular fluid C-reactive protein (CRP) between the SPR treatment group and the control group before treatment and 1 month and 3 months after treatment. Then difference between the two groups was analyzed with SPSS software package.

After treatment with different basic treatments, the periodontal indexes SBI, PD, and CAL were significantly decreased compared with those before treatment, and there was significant difference in gingival crevicular fluid CRP, but there was no significant difference between the two groups. The periodontal index of SBI, PD, and CAL in the control group was gradually increased after 3 months and was not significantly different from that before treatment. The improvement of clinical indicators in the experimental group was more obvious and there was significant difference. CRP in the gingival crevicular fluid of the experimental group and the control group were decreased after a period of periodontal treatment, and there was significant difference before and after treatment. There was also a significant difference in CRP between the experimental group and the control group 3 months after treatment (P<0.01). However, CRP in the gingival crevicular fluid gradually increased in the control group after 3 months, and there was no significant difference between the two groups.

Complete SPR periodontal therapy can control chronic periodontitis effectively, reduce CPR of gingival crevicular fluid, and reduce the systemic inflammatory status of patients. This may have a positive impact on the control of risk factors in patients with coronary heart disease.