Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Food Intake01:30

Regulation of Food Intake

2.9K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
2.9K
Microorganisms in Agriculture and Food industry01:27

Microorganisms in Agriculture and Food industry

1.5K
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
1.5K
Pharmacokinetics: Drug–Food and Drug–Viral Interactions01:26

Pharmacokinetics: Drug–Food and Drug–Viral Interactions

243
A drug interaction occurs when the concurrent use of another drug, food, or an external substance alters the pharmacological activity of a drug. This interaction can modify the action of the original drug, affecting its effectiveness and safety.Drug–food interactions are significant as they impact drug absorption, metabolism, and excretion. For example, grapefruit juice is a well-known disruptor of drug metabolism. It inhibits the cytochrome P450 3A4 enzyme, crucial for the metabolism of...
243
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.9K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.9K
Targets for Drug Action: Overview01:26

Targets for Drug Action: Overview

10.2K
Drugs target macromolecules to modify ongoing cellular processes. Primary drug targets include receptors, ion channels, transporters, and enzymes.
Receptors are either membrane-spanning or intracellular proteins, which upon binding a ligand, get activated and transmit the signal downstream to elicit a response. Drugs bind receptors, either mimicking the action of endogenous ligands or blocking the receptor activity to bring about a modified response. Nearly 35% of approved drugs target the G...
10.2K
Target Cell Response to Hormones01:22

Target Cell Response to Hormones

5.7K
Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
5.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Digital Tools for Information, Communication, Support, and Family Engagement in Adult Intensive Care Units: A Scoping Review.

Healthcare (Basel, Switzerland)·2026
Same author

Immunonutrition in Early Life: The Role of Complementary Feeding, Dietary Patterns, and Nutritional Exposures on the Health of Young Children-An EAACI Scoping Review.

Allergy·2026
Same author

Evidence-Based Clinical Recommendations for the Appropriate Use of Diagnostic Tests in Pediatric Allergology: Focus on Asthma, Rhinoconjunctivitis, and Keratoconjunctivitis Vernal.

Journal of clinical medicine·2026
Same author

Blended and Technology-Enhanced Education in Pediatric Emergency Nursing: A Systematic Review.

Pediatric reports·2026
Same author

Allergic rhinitis and nasal septum deviation in children: cause, consequence, or bidirectional relationship? Insights from the ARHINASD study.

Frontiers in medicine·2026
Same author

Growth and safety of infants with cow's milk allergy receiving a new hydrolyzed rice protein-based formula containing 2-fucosyllactose and lacto-N-neotetraose: protocol for a randomized clinical trial. The RIGHT-GO study.

Frontiers in nutrition·2026

Related Experiment Video

Updated: Jan 30, 2026

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

25.3K

Targeting Food Allergy with Probiotics.

Lorella Paparo1,2, Rita Nocerino1,2, Carmen Di Scala1,2

  • 1Department of Translational Medical Science, University of Naples "Federico II", Naples, Italy.

Advances in Experimental Medicine and Biology
|January 26, 2019
PubMed
Summary

Strategies to combat rising food allergies focus on immune tolerance. Gut microbiota and its metabolites, like butyrate, are key targets for probiotic and postbiotic interventions to restore immune balance.

Keywords:
ButyrateCow’s milk allergyGut microbiotaImmune tolerancePost-bioticsProbiotics

More Related Videos

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

26.6K
Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.5K

Related Experiment Videos

Last Updated: Jan 30, 2026

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

25.3K
Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

26.6K
Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.5K

Area of Science:

  • Immunology
  • Microbiology
  • Allergy Research

Background:

  • Global rise in food allergy prevalence and severity necessitates novel therapeutic strategies.
  • Food allergies stem from impaired immune tolerance, influenced by gut microbiota.
  • Gut dysbiosis is linked to food allergy development, highlighting the gut microbiome's role.

Purpose of the Study:

  • To explore the role of gut microbiota in modulating immune tolerance relevant to food allergies.
  • To investigate the potential of probiotics and postbiotics in restoring immune tolerance.
  • To inform optimal strategies for microbial-based interventions against food allergies.

Main Methods:

  • Review of current scientific literature on gut microbiota, immune tolerance, and food allergies.
  • Analysis of evidence supporting probiotic strain selection, dosage, and timing.
  • Examination of the role of gut microbiota metabolites, such as butyrate, in immune modulation.

Main Results:

  • Gut microbiota composition and function significantly impact immune tolerance.
  • Specific probiotic strains show potential for enhancing immune tolerance mechanisms.
  • Gut microbiota-derived metabolites, like butyrate, are emerging targets for immune stimulation.

Conclusions:

  • Targeting gut microbiota through probiotics or postbiotics offers a promising avenue for managing food allergies.
  • Further research is needed to define optimal microbial interventions for immune tolerance.
  • Understanding metabolite-driven mechanisms, like butyrate production, is crucial for developing effective postbiotic therapies.