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[Derivatives of phenoxyacetamide and antimycotic activity]
G Daidone1, D Raffa, M L Bajardi
1Dipartimento di Chimica e Tecnologie Farmaceutiche, Universita di Palermo.
Il Farmaco; Edizione Scientifica
|September 1, 1988
Abstract:
Novel N-(3-methyl-4-R-isoxazol-5-yl)-2-R1-4-R2-phenoxyacetamides and N-(3-methyl-4-R-isoxazol-5-yl)-2-(2-R1-4-R2-phenoxyacetamido) benzamides were prepared and tested against Candida albicans and Cryptococcus neoformans. The results of the antimicrobial assay showed that the presence of two amidic groups usually enhances antimycotic activity.