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Published on: June 16, 2023
Evaluation of early wound leakage as a risk factor for prosthetic joint infection
Keetie Kremers1, Borg Leijtens1, Simone Camps2
1Department of Orthopedic Surgery, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Insights
Prosthetic joint infections after knee or hip replacement are linked to wound leakage and hematoma. These complications increase dressing changes and hospital stays, highlighting the need for vigilant postoperative care.
Area of Science:
- Orthopedic Surgery
- Infectious Disease
- Patient Safety
Background:
- Prosthetic joint infection (PJI) is a significant complication following total knee arthroplasty (TKA) and total hip arthroplasty (THA).
- Identifying risk factors for PJI is crucial for improving patient outcomes and reducing healthcare burdens.
Purpose of the Study:
- To compare patients with PJI to those with an uncomplicated postoperative course.
- To identify specific risk factors associated with the development of PJI after TKA and THA.
Main Methods:
- A matched case-control study design was employed.
- Data collected included demographics, surgical characteristics, and postoperative events such as hematoma, wound leakage, and length of stay (LOS).
Main Results:
- Patients who developed PJI experienced significantly higher rates of wound leakage (88% vs. 36%) and early wound dressing changes (88% vs. 40%).
- Hematoma formation was more prevalent in the PJI group (44% vs. 10%).
- A strong correlation was found between the number of wound dressing changes and PJI development (p < .001), with PJI patients having a significantly longer LOS (72% vs. 34%, OR 10.5).
Conclusions:
- Early postoperative wound drainage and hematoma formation are direct indicators of PJI risk.
- These factors lead to increased wound care needs and prolonged hospital stays.
- Nurse practitioners play a vital role in early detection of adverse postoperative events, including PJI.
Background And Purpose:
Prosthetic joint infection (PJI) is a serious complication resulting from total knee arthroplasty (TKA) or total hip arthroplasty (THA). In this study, patients with a PJI are compared with patients with an uncomplicated postoperative course to identify relevant risk factors for PJI.
Methods:
A matched case-control study was performed with patients undergoing fast-track, elective unilateral TKA or THA. The following data were collected: demographics, surgery-related characteristics (perioperative blood loss, use of cement, body temperature), and postoperative characteristics (hematoma formation, wound leakage, blood transfusion, length of stay [LOS]).
Conclusions:
When the PJI group was compared with the control group, there was significantly more wound leakage during hospital stay (88% vs. 36%, p = .001) and early wound dressing changes in the first 3 days after surgery (88% vs. 40%, p = .002). Hematoma formation was observed more in the PJI patients group (44% vs. 10%, p = .005). A trend test revealed a significant association between the total number of wound dressing changes and development of PJI (p < .001); 72% of PJI patients had a length of stay of ≥4 days compared with 34% of controls (odds ratio 10.5; 95% CI [2.1-52.3]; p = .004).
Implications For Practice:
Early postoperative wound drainage and hematoma formation directly correlate with PJI. This resulted in a significantly higher number of dressing changes and longer LOS. The nurse practitioner has a central role in postoperative care and is the first to recognize signs of an adverse postoperative clinical course.
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