Related Experiment Video
Updated: Jan 30, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Cardiovascular disease-related medical evacuations, active and reserve components, U.S. Armed Forces, 1 October
Insights
A study of military evacuations found that cardiovascular diseases (CVD) were a significant concern, with hypertension and hyperlipidemia being common pre-existing risk factors among evacuated service members.
Area of Science:
- Military Medicine
- Cardiovascular Health
- Public Health
Background:
- Cardiovascular disease (CVD) poses a significant health challenge for military personnel, particularly during deployment.
- Understanding the prevalence and risk factors of CVD in deployed service members is crucial for operational readiness and healthcare planning.
Purpose of the Study:
- To analyze the incidence and characteristics of cardiovascular disease (CVD)-related medical evacuations from the U.S. Central Command (CENTCOM) area of responsibility.
- To identify pre-deployment CVD risk factors among evacuated service members.
Main Methods:
- Retrospective analysis of medical evacuation data from October 1, 2001, to December 31, 2017.
- Inclusion criteria: Service members evacuated from the CENTCOM AOR with a subsequent diagnosis of CVD in a fixed medical facility.
- Data collected included demographics, pre-deployment CVD risk factors (hypertension, hyperlipidemia, obesity, diabetes), and number of risk factors.
Main Results:
- A total of 697 service members were medically evacuated for CVD.
- The majority evacuated were male (94.7%).
- Pre-deployment risk factors included hypertension (33.9%) and hyperlipidemia (34.9%); 26.1% had more than one risk factor.
Conclusions:
- Cardiovascular disease is a notable reason for medical evacuation among U.S. service members in the CENTCOM AOR.
- Pre-existing hypertension and hyperlipidemia are prevalent risk factors, highlighting the need for targeted screening and management strategies.
- Further research and in-theater interventions are necessary to mitigate CVD morbidity in military personnel.
Abstract:
From 1 October 2001 through 31 December 2017, a total of 697 medical evacuations of service members from the U.S. Central Command (CENTCOM) area of responsibility were followed by at least one medical encounter in a fixed medical facility outside the operational theater with a diagnosis of a cardiovascular disease (CVD). The vast majority of those (n=660; 94.7%) evacuated were males. More than a third of CVD-related evacuations (n=278, 39.9%) occurred in service members 45 years of age or older; slightly more than half (n=369; 52.9%) occurred in reserve or guard members. The most common CVD risk factors which had been diagnosed among evacuated service members prior to their deployment were hypertension (n=236; 33.9%) and hyperlipidemia (n=241; 34.9%). Much lower percentages had been previously diagnosed with obesity (n=74, 10.6%) or diabetes (n=21, 3.0%). More than 1 in 4 service members with a CVD-related medical evacuation had been diagnosed with more than one risk factor (n=182, 26.1%). Both limitations to the data available and strategies to reduce CVD morbidity in theater are discussed.
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