Related Experiment Video
Updated: Jan 30, 2026

Reliable Isolation of Central Nervous System Microvessels Across Five Vertebrate Groups
Published on: January 12, 2020
Vertebral artery triplication
1Division of Interventional Neuroradiology, The Johns Hopkins Hospital, 1800 E Orleans Street, Baltimore, MD, 21287, USA. phg@jhmi.edu.
Purpose:
To report an extremely rare vertebral artery (VA) origin configuration.
Methods:
Angiographic and MRI features of a VA triplication in a child are presented.
Results:
The VA trifurcation was the result of the simultaneous persistence of the 4th, 5th and 6th primitive cervical intersegmental arteries, respectively, reaching the transverse canal at C4, C5 and C6. A contralateral VA duplication was noted as well.
Conclusion:
A previously undocumented instance of VA triplication is presented. Knowledge of such variations is important for the planning of diagnostic and therapeutic cervicocranial angiography and the understanding of unusual images on noninvasive imaging studies. This type of anomaly also represents a risk factor for arterial dissection.
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