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Updated: Jan 30, 2026

Anterior Cervical Discectomy and Fusion in the Ovine Model
Published on: October 5, 2009
Inciting Events Associated With Cervical Radiculopathy.
James Rainville1,2, Moorice Caparó1,3, Eric Laxer4
1Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA.
Most cervical radiculopathy (CR) cases begin without a specific trigger, with two-thirds of patients reporting symptom onset upon waking or without a memorable event. Physical inciting events do not impact CR severity.
Area of Science:
- Neurology
- Orthopedics
- Radiology
Background:
- Cervical radiculopathy (CR) involves neck, shoulder, and arm pain with sensory/motor deficits.
- Degenerative spine pathology causing nerve root impingement is a common cause, visualized by MRI or CT.
- Factors initiating CR onset have not been previously explored.
Purpose of the Study:
- To identify and categorize patient-reported inciting events linked to CR onset.
- To determine the frequency of various inciting events in CR patients with confirmed pathology.
- To analyze the correlation between inciting events and CR clinical characteristics.
Main Methods:
- Prospective observational case series design.
- 107 patients with MRI/CT-confirmed cervical disk herniation or foraminal stenosis were included.
- Inciting events were categorized by severity; clinical data and pain intensity were recorded.
Main Results:
- Two-thirds of patients experienced CR onset without a specific memorable event (e.g., waking with symptoms).
- One-third of patients reported physical activity or trauma as inciting events.
- CR clinical characteristics were not significantly influenced by the category of inciting event.
Conclusions:
- The majority of cervical radiculopathy cases with confirmed spinal pathology arise spontaneously.
- Physical inciting events do not appear to alter the clinical severity of cervical radiculopathy.
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