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Evaluating the Function of the Foot Core System in the Elderly

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[Subclinical Hypothyroidism on the Elderly].

Sofia Macedo Silva¹, Alexandra Carvalho¹, Maria Lopes-Pereira²

¹Unidade de Saúde Familiar Esposende Norte. Esposende. Portugal.

Acta Medica Portuguesa

|January 27, 2019

Summary

This summary is machine-generated.

Subclinical hypothyroidism impacts the elderly differently, often requiring no treatment for mild cases. An individualized approach and long-term monitoring are recommended for older adults.

Keywords:

Aged Hypothyroidism/diagnosis Reference Values Thyroid Function Tests

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Area of Science:

Endocrinology
Geriatrics

Background:

Subclinical hypothyroidism (SCH) involves elevated thyroid-stimulating hormone (TSH) with normal thyroid hormones.
SCH may have multiorgan effects, with potential age-related differences in elderly populations.

Purpose of the Study:

To review the diagnosis and treatment of subclinical hypothyroidism in the elderly.
To explore age-specific considerations for managing SCH in individuals over 65.

Main Methods:

A narrative bibliographical review of electronic databases.
Analysis of case studies and clinical trial data.

Main Results:

SCH appears to have a reduced impact in the elderly, especially those over 80-85.
TSH levels naturally increase with age.
Treatment for TSH between 4.5-10.0 mIU/L is not consistently beneficial, as shown in the TRUST study.

Conclusions:

Reference ranges and age are critical factors influencing SCH outcomes.
Non-treatment of mild SCH (4.5-7.0 mIU/L) is generally agreed upon for the elderly, particularly those over 80.
Individualized treatment and monitoring are essential for elderly patients with SCH, with a lower threshold (4.5 mIU/L) for intervention in specific cases (e.g., positive antibodies).