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Updated: Jan 30, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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Published on: July 26, 2017

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The nitrone spin trap 5,5‑dimethyl‑1‑pyrroline N‑oxide binds to toll-like receptor-2-TIR-BB-loop domain and dampens

Marcos D Muñoz1, Lucas J Gutierrez2, Sandrine Delignat3

  • 1Laboratory of Experimental and Translational Medicine, IMIBIO-SL-School of Chemistry, Biochemistry and Pharmacy, National University of San Luis-CONICET, San Luis, 5700 San Luis, Argentina.

Biochimica Et Biophysica Acta. Molecular Basis of Disease
|January 27, 2019
PubMed

Keywords:
BB-loopDMPOMechanism-based drugSignal transductionTIR domainTLR2

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