Related Experiment Video

Updated: Jan 30, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

8.1K

Extracranial Internal Carotid Artery Aneurysm in a Patient with Marfan Syndrome

George S Sfyroeras1, Eleni Aliki Nikolopoulou1, Konstantinos G Moulakakis1

  • 1Department of Vascular Surgery, University of Athens Medical School, Attikon University Hospital, Athens, Greece.

Annals of Vascular Surgery
|January 28, 2019
PubMed

Insights

Extracranial internal carotid artery (ICA) aneurysms are rare, especially in Marfan syndrome (MS). This case report details a successful surgical treatment for MS-associated extracranial ICA aneurysm, adding to limited literature.

Area of Science:

  • Vascular Surgery
  • Genetics
  • Connective Tissue Disorders

Background:

  • Extracranial internal carotid artery (ICA) aneurysms are uncommon, typically linked to atherosclerosis.
  • Marfan syndrome (MS) is a genetic disorder affecting connective tissue, primarily due to fibrillin-1 mutations.
  • MS commonly presents with aortic aneurysms, lens dislocation, and skeletal overgrowth.

Observation:

  • A 62-year-old female patient with known Marfan syndrome presented with an extracranial ICA aneurysm.
  • This specific combination of Marfan syndrome and extracranial ICA aneurysm is exceptionally rare in medical literature.
  • Only 10 previous cases of Marfan syndrome with extracranial ICA aneurysms have been documented.

Findings:

  • The patient underwent successful surgical intervention, including aneurysmectomy and end-to-end anastomosis.
  • The surgical outcome was favorable, indicating the viability of this treatment approach.
  • This case contributes to the understanding of rare vascular manifestations in Marfan syndrome.

Implications:

  • Highlights the importance of considering rare vascular pathologies in patients with connective tissue disorders like Marfan syndrome.
  • Suggests that surgical repair, such as aneurysmectomy and anastomosis, can be effective for extracranial ICA aneurysms in MS patients.
  • Emphasizes the need for further research and case reporting to better comprehend and manage these infrequent presentations.

More Related Videos

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit06:11

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit

Published on: May 14, 2020

2.8K
Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery06:41

Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

Published on: January 31, 2017

11.6K

Related Concept Videos

Internal Energy02:00

Internal Energy

The total of all possible kinds of energy present in a substance is called the internal energy (U), sometimes symbolized as E. Suppose a system with initial internal energy, Uinitial, undergoes a change in energy (transfer of work or heat), and the final internal energy of the system is Ufinal. Change in internal energy equals the difference between Ufinal and Uinitial.
36.7K
Internal Energy01:29

Internal Energy

The internal energy of a thermodynamic system is the sum of the kinetic and potential energies of all the molecules or entities in the system. The kinetic energy of an individual molecule includes contributions due to its rotation and vibration, as well as its translational energy. The potential energy is associated only with the interactions between one molecule and the other molecules of the system. Neither the system's location nor its motion is of any consequence as far as the internal...
7.0K
Internal Receptors01:31

Internal Receptors

Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
74.6K
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
408
International System of Units01:29

International System of Units

The International System of Units, known as the SI system, is a universally accepted measurement system recognized and used worldwide. The SI system is based on a set of three base units considered absolute, and their values do not change with location. These base units are meters, kilograms, and seconds.
Prefixes are used to define both larger and smaller quantities in the SI system. For example, milli, micro, and nano define smaller quantities, while kilo, mega, and giga are used to define...
5.1K
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
468