Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Marine Pinturaud1, Michèle Vasseur2, Pascal Odou2

  • 1Centre Hospitalier Universitaire de Lille, Institut de Pharmacie, 59037 Lille, France.

Bulletin Du Cancer
|January 29, 2019
PubMed
Summary

Hospital pharmacists are crucial for managing advanced therapy medicinal products like Chimeric Antigen Receptor T-cells (CART). Their role ensures quality and safety throughout the CART treatment process, including patient follow-up and staff training.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiorespiratory tolerance of continuous dexmedetomidine infusion in preterm and term newborn infants: a retrospective cohort study.

European journal of pediatrics·2026
Same author

Effect of Pharmacy Student Peer Supervision on the Accuracy of Admission Medication Reconciliation: Prospective Pre-Post Observational Study.

JMIR human factors·2026
Same author

Hospital production of a 1% propofol-cyclodextrin formulation to address drug shortages: a proof of concept.

European journal of hospital pharmacy : science and practice·2026
Same author

Environmentally responsible use of hospital infusion systems: a systematic review of the literature.

European journal of hospital pharmacy : science and practice·2025
Same author

The French Experience of Pharmacists and CAR T-Cells: A Study of the French Society of Oncology Pharmacy (SFPO).

Hematological oncology·2025
Same author

Interpretable one-class classification framework for prescription error detection using BERT embeddings and dimensionality reduction.

Computers in biology and medicine·2025

Area of Science:

  • Oncology
  • Cellular Therapy
  • Pharmacology

Background:

  • Chimeric Antigen Receptor T-cells (CART) are a novel class of Advanced Therapy Medicinal Products (ATMPs) and gene therapy products.
  • Their unique nature as genetically modified organisms necessitates specialized handling and management within hospitals.
  • Current pharmacy practices require significant adaptation to accommodate CART therapy.

Purpose of the Study:

  • To identify and detail the essential roles of hospital pharmacists in managing CART products.
  • To outline the necessary adaptations in hospital pharmacy circuits for safe and effective CART administration.
  • To emphasize the pharmacist's contribution to patient safety and treatment quality.

Main Methods:

  • Review of the CART therapy pathway within a hospital setting.
Keywords:
Chimeric Antigen Receptor T cells (CART)Circuit du médicamentDrug circuitGene therapyHospital pharmacistLymphocytes T exprimant unPharmacien hospitalierRécepteur Chimérique à l’Antigène (CART)Thérapie génique

Related Experiment Videos

  • Analysis of specific challenges and requirements for pharmacy involvement.
  • Identification of necessary staff training and infrastructural adjustments.

    • Main Results:

    • Hospital pharmacists play a pivotal role in establishing and overseeing the CART management circuit.
    • Adaptations include specialized skills, team reorganization, and staff training.
    • Pharmacists are vital for ensuring quality, safety, and effective patient follow-up.

    Conclusions:

    • The integration of hospital pharmacists is fundamental for the successful implementation of CART therapy.
    • Proactive adaptation of pharmacy services is required to meet the demands of these complex treatments.
    • Pharmacists are key to optimizing patient outcomes and safety in CART therapy.