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Differences in left ventricular geometry in hypertensive African-Europeans and Caucasian patients

Laurence Ejiofor1, Concetta Di Nora2, Eugenio Cervesato1

  • 1Cardiology Department, ARC Ospedale di Pordenone, Italy.

European Journal of Internal Medicine
|January 29, 2019
PubMed

Insights

Hypertensive African-Europeans show higher rates of left ventricular (LV) concentric remodeling and hypertrophy compared to Caucasians. These findings highlight race-related differences in LV geometry among hypertensive individuals.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Echocardiography

Background:

  • Race-related differences in left ventricular (LV) geometry exist in hypertensive patients.
  • Concentric remodeling is common in hypertensive African-Americans, potentially impacting prognosis.
  • Limited data exists on LV remodeling patterns in African migrants in Europe.

Purpose of the Study:

  • To determine the prevalence of LV remodeling patterns in hypertensive African-Europeans.
  • To compare LV geometry in hypertensive African-Europeans with hypertensive Caucasians.

Main Methods:

  • A descriptive study involving 135 treated hypertensive African-Europeans and 128 hypertensive Caucasians.
  • Transthoracic echocardiography was used to assess LV geometry.
  • Patients were classified into four geometric patterns based on LV mass index (LVMi) and relative wall thickness (RWT).

Main Results:

  • African-Europeans exhibited higher relative wall thickness and interventricular septum thickness than Caucasians.
  • The prevalence of concentric remodeling and concentric hypertrophy was significantly higher in African-Europeans (81%) compared to Caucasians (67%).
  • No significant difference in LV mass index was observed between the groups.

Conclusions:

  • Significant differences in LV geometry exist between treated hypertensive African-Europeans and Caucasians.
  • Hypertensive African-Europeans demonstrate a higher predisposition to adverse LV remodeling patterns.
  • Findings suggest potential variations in LV geometry between African-Europeans and African-Americans.
Abstract

Keywords:
Arterial hypertensionLeft ventricular geometryPrimary prevention

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