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Author Spotlight: Double Posteromedial Approach for Treating Posterior Cruciate Ligament Cysts
Published on: October 20, 2023
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[Uncommon mycoses]
Lourdes Viñuela1, Marta Domínguez-Gil1, Mónica de Frutos1
1Servicio de Microbiología y Parasitología, Hospital Universitario Río Hortega, Valladolid, España.
Revista Iberoamericana De Micologia
|January 29, 2019
Summary
This study highlights rare fungal wound infections in an immunocompetent individual. Determining antifungal sensitivity is crucial for treating these emerging infections.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Wound Management
Background:
- Fungal infections can occur in severe wounds contaminated with organic material or soil, even in immunocompetent individuals.
- Rare fungal pathogens can cause severe infections, necessitating a better understanding of their epidemiology and antifungal sensitivity.
Observation:
- Four molds (Lichtheimia corymbifera, Scedosporium boydii, Fusarium solani, Purpureocillium lilacinum) were isolated from an immunocompetent woman's wounds after a road accident.
- In vitro antifungal resistance profiling was performed using Epsilometer (Etest™) with five agents: voriconazole, posaconazole, itraconazole, anidulafungin, and amphotericin B.
Findings:
- The isolated molds exhibited specific in vitro resistance patterns to the tested antifungal agents.
- Results were consistent with previously reported cases in the literature, indicating a potential trend in resistance.
Implications:
- Early aggressive surgical intervention, appropriate antifungal therapy, and frequent debridement of necrotic tissue are essential for managing filamentous fungal infections.
- Determining the antifungal sensitivity of all involved molds is critical for effective treatment and understanding these increasingly prevalent, rare pathogens.
Keywords:
Fusarium solaniImmunocompetentInmunocompetenteLichtheimia corymbiferaPurpureocillium lilacinumScedosporium boydiiScedosporiumboydii
