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Published on: August 7, 2017
Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
Elizabeth Pan1, Eric Hsieh1, Caroline Piatek2
1Department of Medicine, Keck School of Medicine of USC, Los Angeles, California, USA.
Abstract:
Thrombocytopenia is a frequent complication of cancer may be due to a variety of causes including malignancy itself, acute disease processes, or cancer therapy. Systemic cancer therapy is the most common cause of thrombocytopenia in cancer patients observed nearly two-thirds of patients with solid tumors. Thrombocytopenia with traditional chemotherapy agents is most frequently the result of megakaryocyte cytotoxicity. Oxaliplatin is a platinum derivative commonly used in gastrointestinal malignancies and is associated with drug-induced immune thrombocytopenia.
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