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Lack of DNA synthesis inhibitory activity in an immunosuppressor obtained from spleen
Cell and Tissue Kinetics
|May 1, 1978
A tissue extract derived from bovine spleen which is an immunosuppressor in vivo inhibits the incorporation of the two DNA pyrimidine nucleosides but does not inhibit the incorporation of purine nucleosides. The results indicate that the immunosuppressive action of the spleen extract is not mediated via inhibition of cell division.
A tissue extract derived from bovine spleen which is an immunosuppressor in vivo inhibits the incorporation of the two DNA pyrimidine nucleosides but does not inhibit the incorporation of purine nucleosides. The results indicate that the immunosuppressive action of the spleen extract is not mediated via inhibition of cell division.