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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
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Postural Control Complexity and Fatigue in Minimally Affected Individuals with Multiple Sclerosis
Felipe B Santinelli1, Fabio A Barbieri1, Carina F Pinheiro2
1a Human Movement Research Laboratory (MOVI-LAB), Department of Physical Education, Graduate Program in Movement Sciences , São Paulo State University (UNESP)-Campus Bauru , Brazil .
Journal of Motor Behavior
|January 29, 2019
Summary
Fatigue reduces postural control complexity in people with multiple sclerosis (PwMS) and healthy individuals. Minimally affected PwMS showed similar postural complexity and fatigue effects compared to controls.
Area of Science:
- Neurology
- Rehabilitation Science
- Biomedical Engineering
Background:
- Multiple Sclerosis (MS) is a demyelinating disease affecting the central nervous system.
- Fatigue is a common and debilitating symptom in people with MS (PwMS).
- Postural control is crucial for daily activities and can be impaired in PwMS.
Purpose of the Study:
- To investigate the impact of fatigue on postural control complexity in minimally affected PwMS.
- To compare postural control complexity between PwMS and non-MS controls before and after a fatigue protocol.
- To examine the influence of visual conditions (saccades and fixation) on postural control complexity.
Main Methods:
- Thirteen minimally affected PwMS and 12 non-MS controls participated.
- Postural control was assessed using a force platform during quiet stance.
- Multiscale entropy analysis was employed to quantify postural complexity.
- A fatigue protocol was administered before post-test measurements.
Main Results:
- Fatigue significantly reduced postural complexity in the medial-lateral direction for both PwMS and controls (p <0.007).
- No significant differences in postural complexity were observed between PwMS and controls.
- Visual conditions did not significantly alter postural complexity or the effects of fatigue.
Conclusions:
- Minimally affected PwMS exhibit comparable postural control complexity to non-MS controls.
- Fatigue similarly impacts postural control complexity in both PwMS and healthy individuals.
- Postural control complexity is a sensitive measure affected by fatigue, regardless of MS status.
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