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[Isolated and transient hyperphosphatasemia in young children].
J J Benichou1, J Ribier, J P Dommergues
1L'Hôpital de Jour, Département de Pédiatrie, Hôpital de Bicêtre Le Kremlin Bicêtre.
Archives Francaises De Pediatrie
|November 1, 1988
Summary
Transient hyperphosphatasemia in infants is a temporary condition with elevated bone and liver enzyme activity. This benign finding requires no further investigation, preventing unnecessary medical procedures.
Area of Science:
- Pediatric Endocrinology
- Clinical Biochemistry
Background:
- Transient hyperphosphatasemia is a rare condition characterized by elevated serum alkaline phosphatase (SAP) levels.
- The condition typically presents in infants and young children without apparent symptoms.
Observation:
- A case of transient and isolated hyperphosphatasemia is reported in a 33-month-old infant.
- The infant was asymptomatic, with significant increases observed in both bone and liver enzyme fractions.
Findings:
- The hyperphosphatasemia was transient and benign, resolving spontaneously.
- The underlying pathophysiology remains unclear, necessitating further research.
Implications:
- Awareness of this benign condition is crucial for clinicians.
- Knowledge of transient hyperphosphatasemia can prevent unnecessary diagnostic investigations and associated costs.