Related Experiment Videos
[Isolated and transient hyperphosphatasemia in young children]
J J Benichou1, J Ribier, J P Dommergues
1L'Hôpital de Jour, Département de Pédiatrie, Hôpital de Bicêtre Le Kremlin Bicêtre.
Insights
Transient hyperphosphatasemia in infants is a temporary condition with elevated bone and liver enzyme activity. This benign finding requires no further investigation, preventing unnecessary medical procedures.
Area of Science:
- Pediatric Endocrinology
- Clinical Biochemistry
Background:
- Transient hyperphosphatasemia is a rare condition characterized by elevated serum alkaline phosphatase (SAP) levels.
- The condition typically presents in infants and young children without apparent symptoms.
Observation:
- A case of transient and isolated hyperphosphatasemia is reported in a 33-month-old infant.
- The infant was asymptomatic, with significant increases observed in both bone and liver enzyme fractions.
Findings:
- The hyperphosphatasemia was transient and benign, resolving spontaneously.
- The underlying pathophysiology remains unclear, necessitating further research.
Implications:
- Awareness of this benign condition is crucial for clinicians.
- Knowledge of transient hyperphosphatasemia can prevent unnecessary diagnostic investigations and associated costs.
Abstract:
This report concerns a transient and isolated hyperphosphatasemia in a 33 month-old infant. Such a case is asymptomatic and benign. There is an important increase in enzymatic activity which includes both fractions (bone and liver). Pathophysiology is still unclear. This biological data is worth being known in order to avoid useless and always normal investigations.